Trials
COoling in Acute STroke II (COAST II)
A randomised, monocenter study on endovascular cooling to 35°C following the induction of hypothermia by ice cold saline. Patients included into the study are standard thrombolysed patients (time window 3 hours)
contact rainer.kollmar@uk-erlangen.de
Hypothermia for Acute Ischaemic Stroke Trial - Edinburgh (HAIST-E)
A randomised pilot study of surface cooling to 35ºC or 33ºC degrees for 12 or 24 hours, with MR spectroscopy measurement of brain temperature
contact malcolm.macleod@ed.ac.uk
Hypothermia for Acute Ischaemic Stroke Trial - Utrecht (HAIST-U)
A randomised pilot study of surface cooling to 35ºC or 33ºC degrees for 12 or 24 hours
contact H.B.vanderWorp@umcutrecht.nl
Malmö Acute Stroke Cooling Trial (MASCOT)
A randomised pilot study of surface cooling to 33ºC for 24 hours in ventilated patients who have failed to improve with conventional therapy
contact Jesper.Petersson@skane.se or derkkrieger@yahoo.com
Mild Hypothermia in Acute Ischemic Stroke: Safety and Feasibility Study (MHAIS)
A randomised pilot study of surface cooling to 35C for 12 hours in patients who have failed to improve within 2 hrs of tPA treatment.
contact katja.piironen@hus.fi